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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
INTS12
All Species:
24.24
Human Site:
S376
Identified Species:
44.44
UniProt:
Q96CB8
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96CB8
NP_001135943.1
462
48808
S376
G
K
T
G
L
S
R
S
V
S
C
D
N
V
S
Chimpanzee
Pan troglodytes
XP_517380
462
48786
S376
G
K
T
G
L
S
R
S
V
S
C
D
N
V
S
Rhesus Macaque
Macaca mulatta
XP_001084188
462
48791
S376
G
K
T
G
L
S
R
S
V
S
C
D
N
V
S
Dog
Lupus familis
XP_545012
788
84125
S702
G
K
T
G
L
S
R
S
V
S
C
D
N
V
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9D168
461
48550
S375
G
K
T
G
L
S
R
S
V
S
C
D
N
V
S
Rat
Rattus norvegicus
Q68FR3
461
48459
S375
G
K
T
G
L
S
R
S
V
S
C
D
N
V
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511131
200
19036
P129
I
P
S
P
E
Q
L
P
G
P
G
G
G
N
P
Chicken
Gallus gallus
XP_420500
509
53231
S421
T
L
G
K
T
T
L
S
R
S
V
S
S
D
N
Frog
Xenopus laevis
Q6DJM6
464
48894
R373
L
G
K
T
G
L
S
R
S
M
S
S
D
N
V
Zebra Danio
Brachydanio rerio
Q6IQU7
479
49572
L378
K
A
P
P
P
L
T
L
G
K
Q
V
L
S
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651507
328
34315
K257
S
S
S
K
H
G
H
K
S
S
S
S
S
S
S
Honey Bee
Apis mellifera
XP_393298
287
32118
N216
S
P
K
T
V
I
E
N
K
S
K
E
Q
K
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001195035
333
36996
R262
E
G
P
E
A
A
E
R
A
A
V
D
V
R
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
98.9
54.9
N.A.
91.3
90.6
N.A.
29
73.2
67.4
60.1
N.A.
22.5
23.5
N.A.
25.1
Protein Similarity:
100
99.7
99.7
56.3
N.A.
95.8
95.4
N.A.
32.6
79.1
76.7
72.4
N.A.
39.3
37.4
N.A.
38.7
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
0
13.3
0
0
N.A.
13.3
6.6
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
6.6
33.3
6.6
0
N.A.
26.6
26.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
8
8
0
0
8
8
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
47
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
54
8
8
0
% D
% Glu:
8
0
0
8
8
0
16
0
0
0
0
8
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
47
16
8
47
8
8
0
0
16
0
8
8
8
0
0
% G
% His:
0
0
0
0
8
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% I
% Lys:
8
47
16
16
0
0
0
8
8
8
8
0
0
8
8
% K
% Leu:
8
8
0
0
47
16
16
8
0
0
0
0
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
0
0
0
0
47
16
8
% N
% Pro:
0
16
16
16
8
0
0
8
0
8
0
0
0
0
8
% P
% Gln:
0
0
0
0
0
8
0
0
0
0
8
0
8
0
0
% Q
% Arg:
0
0
0
0
0
0
47
16
8
0
0
0
0
8
8
% R
% Ser:
16
8
16
0
0
47
8
54
16
70
16
24
16
16
54
% S
% Thr:
8
0
47
16
8
8
8
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
8
0
0
0
47
0
16
8
8
47
16
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _